Methylsulfonylmethane (MSM) is a chemical that occurs naturally in humans, as well as some green plants and animals.

According to the Food and Drug Administration (FDA), MSM is considered safe at dosages under 4,000 milligrams (mg) per kilogram (kg) per day and in energy bars at levels up to 30,000 mg/kg. MSM supplements are available in capsule or powder form. Taking more MSM than directed does not appear to provide better results.

### Methyl Sulfonyl Methane (MSM): Definition, Benefits, Side Effects, and Origin

Methyl sulfonyl methane (MSM) is a naturally occurring compound that contains sulfur. Found in small amounts in various foods and beverages, MSM has gained popularity as a dietary supplement, particularly for its purported health benefits related to joint health and inflammation. This article provides an overview of MSM, including its definition, benefits, potential side effects, and origin.

#### Definition

Methyl sulfonyl methane is an organic sulfur compound, often marketed as a supplement to support joint health, reduce inflammation, and promote overall wellness. It is a colorless, odorless solid that is soluble in water and has been used in both alternative medicine and as a nutritional supplement.

#### Benefits of Methyl Sulfonyl Methane

1. **Joint Health**: MSM is frequently used to alleviate symptoms of osteoarthritis and joint pain. It may help reduce inflammation and improve joint function, potentially leading to decreased pain and increased mobility.

2. **Anti-Inflammatory Properties**: Research suggests that MSM possesses anti-inflammatory effects, which can be beneficial for various inflammatory conditions, including arthritis.

3. **Muscle Recovery**: Athletes often use MSM for its potential to reduce muscle soreness and speed up recovery after intense physical activity. Some studies indicate that it may help decrease oxidative stress and inflammation following exercise.

4. **Skin Health**: MSM is also used in skincare products due to its purported ability to enhance skin hydration and improve the appearance of skin conditions such as acne or eczema.

5. **Allergy Relief**: Some anecdotal evidence suggests that MSM may help alleviate symptoms of seasonal allergies by reducing inflammation in the respiratory tract.

#### Side Effects of Methyl Sulfonyl Methane

While MSM is generally considered safe for most people, some may experience side effects, including:

1. **Gastrointestinal Issues**: Some users report mild stomach upset, bloating, or diarrhea when taking MSM, especially at higher doses.

2. **Allergic Reactions**: Although rare, some individuals may have allergic reactions to MSM, which could manifest as skin rashes or itching.

3. **Headaches**: A few users have reported headaches after taking MSM, though the incidence is low.

As with any supplement, it is advisable to consult with a healthcare provider before starting MSM, particularly for individuals with existing health conditions or those taking medications.

#### Origin of Methyl Sulfonyl Methane

MSM is found naturally in small amounts in various foods, including fruits, vegetables, grains, and milk. It can also be synthesized in laboratories. The production of MSM typically involves the oxidation of DMSO (dimethyl sulfoxide), a compound that has been used in medical applications for its solvent properties. MSM can be isolated and purified for use in dietary supplements.

#### Conclusion

Methyl sulfonyl methane is a sulfur-containing compound with a variety of potential health benefits, particularly for joint health and inflammation. While generally well-tolerated, users should be aware of possible side effects and consult a healthcare professional for guidance, especially if they have underlying health conditions. As interest in natural supplements continues to grow, MSM remains a popular choice for those seeking to enhance their overall well-being and manage joint discomfort.